HIGHLIGHTS OF EXPERIENCE
- Research and Development in Cancer Pharmacology leading to over several international patents.
- Undergraduate teaching in the areas of Chemistry, Biochemistry. Biology, and Science Education.
- Development of two lines of patented immunomodulatory anti-neoplastic compounds.
- Cancer research experience: SanRx Pharmaceuticals, San Diego Research, California State Universities - Bakersfield and San Diego, La Jolla Cancer Research Foundation, UCLA Dept. of Chemistry, The Salk Institute.
Ph.D., Education: 1985, University of California, Santa Barbara
C.Phil., Biochemistry: 1978, University of California, Los Angeles
B.S., Biochemistry: 1974, University of California, Los Angeles
Moheno, P., Pfleiderer, W., Dipasquale, A. G., Rheingold, A. L., and Fuchs, D. 2008. Pterin based therapies for inflammation conditions. United States Provisional Patent Application. (Filed: Jan. 18, 2008; world-wide filings)
Moheno P. and Pfleiderer, W. 2010. Dipterinyl calcium pentahydrate (DCP) and therapeutic methods based thereon. United States Patent 7,662,820. (Filed: Oct. 30, 2007; world-wide filings)
Moheno, P. 2006. Novel pterin antineoplastic agents. Japanese Patent Application.
Moheno, P. 2002. Pterin antineoplastic agents. United States Patent 6,358,953.
Moheno, P. 1996. Anti-neoplastic compositions and methods for application thereof. United States Patent 5,534,514.
Academically Reviewed Books
Moheno, P.B.B. (1996). Educating Our 21st Century Adventurers. University Press of America, Inc.
Manuscripts and Articles in Refereed Journals
Nikoulina SE, Fuchs D, Moheno P. Effect of orally administered dipterinyl calcium pentahydrate on oral glucose tolerance in diet-induced obese mice. Diabetes Metab Syndr Obes. 2012;5:43-7. Epub 2012 Feb 24. PubMed PMID: 22419880; PubMed Central PMCID: PMC3299552.
Moheno P., Morrey J, Fuchs D. Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice. J Transl Med. 2010 Mar 31;8(1):32. [Epub ahead of print] PubMed PMID: 20356392.
Moheno P., Pfleiderer W, Fuchs D. Plasma Cytokine Concentration Changes Induced by the Antitumor Agents Dipterinyl Calcium Pentahydrate (DCP) and Related Calcium Pterins. Immunobiology 2009;214:135-141.
Moheno, P., Pfleiderer, W, Fuchs, D. Plasma Cytokine Changes Induced by the Antitumor Agents Dipterinyl Calcium Pentahydrate (DCP) and Related Calcium Pterins. Pteridines 2008;19:49.
Moheno, P., Pfleiderer, W., Dipasquale, A. G., Rheingold, A. L., and Fuchs, D. Cytokine and IDO metabolite changes effected by calcium pterin during inhibition of MDA-MB-231 xenograph tumors in nude mice. Int J Pharm 2008;355:238-248.
Moheno P., Winkler C., Pfleiderer W., Barral A.M., Scuderi, R., Carlson J. Fuchs D. Mechanism of Action Studies with the Antitumor Agent Calcium-pterin. Pteridines 2007;18:50.
Winkler C., Schroecksnadel K., Moheno P., Meerbergen E., Schennach H., Fuchs D. Calcium-pterin suppresses mitogen-induced tryptophan degradation and neopterin production in peripheral blood mononuclear cells. Immunobiology 2006;211:779-784.
Moheno P.B.B., Winkler C., Fuchs D., Ryan J.C., Meerbergen E.J. Role of calcium pterin in natural killer (NK) cell activation and indoleamine 2,3-dioxygenase (IDO) modulation for antitumor activity. Pteridines 2005;16:140.
Moheno P.B.B. Calcium pterin as an antitumor agent. The International Journal of Pharmaceutics 2004:271;293-300.
Stea B., Backlund Jr. P.S., Berkey (Moheno) P.B., Cho A.K., Halpern B.C., Halpern R.M. and Smith R.A. Folate and pterin metabolism by cancer cells in culture. Cancer Research 1978:38;2378-2384.
Manuscripts and Articles in Refereed Journals
Moheno, P.B.B. (1997). Forward to The Place of Confluent Education in the Human Potential Movement: A Historical Perspective by Shapiro, S.B. University Press of America, Inc.
Shapiro, S.B. and Moheno, P.B.B. (1996). Professed Instructional Values Versus Ratings of Student Teachers' Behavior During Classes in Mathematics and Science. Psychological Reports, 79, 796-798.
Moheno, P.B.B. (1993). "Toward a Fully Human Science Education: An Exploratory Study of Prospective Teachers' Attitudes Toward Humanistic Science Education." International Journal of Science Education, 15, 95-106.
Moheno, P.B.B. (1991). "Furthering Elementary Science Education." Catalyst for Change, 21, 8-12.
Moheno, P.B.B. (1989). "Classroom and curriculum management issues for humanistic and confluent teachers". The Journal of Humanistic Education and Development, 27, 98-104.
Moheno, P.B.B. (1987). "An observational instrument to measure humanistic classroom interaction patterns". The Journal of Humanistic Education and Development, 26, 32-46.