Dr. Jose MendozaDr. Mendoza is interested in deciphering how cells are protected by the "stress proteins".
These proteins protect cells from the adverse effects of stressful conditions (i.e.
heat, oxidation, acid, etc.). He is currently investigating the roles of the stress
proteins in the survival of Helicobacter pylori in the stomach acidic environment. About 50% of the human population is infected
with this bacterium and chronic infection can, in certain individuals, give rise to
gastric ulcers and gastric cancer. This research involves a combination of biochemical
and biophysical analyses of wild-type and mutant proteins.
Ph.D. Biochemistry, University of Texas Health Science Center at San Antonio, 1992
M.S. Organic Chemistry, University of Texas at El Paso, 1982
B.S. Chemistry, Instituto Tecnologico y de Estudios Superiores de Monterrey (Mexico),
PublicationsMendoza, J.A., Rogers, E., Lorimer, G.H., and Horowitz, P.M. (1991) Chaperonins Facilitate the
in Vitro Folding of Monomeric Mitochondrial Rhodanese. J. Biol. Chem. 266, 13044-13049.
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